| Titre : | Carbapenem prescriptions : Compliance with guidelines in a pediatric hospital (2023) |
| Auteurs : | Clara Cebron, Auteur ; Mina Smiljkovic, Auteur ; Lucas Percheron, Auteur ; Yvan Caspar, Auteur ; Julie Arata-Bardet, Auteur ; Guillaume Mortamet, Auteur ; Marie Martinod, Auteur |
| Type de document : | Article |
| Dans : | Archives de pédiatrie (Vol. 30, n°5, juillet 2023) |
| Article en page(s) : | 302-306 |
| Langues: | Français |
| Catégories : | |
| Résumé : |
Background : This study aimed to describe the use of carbapenems in a pediatric tertiary center and to assess its compliance with national and local guidelines.
Methods : This retrospective study focused on children who received at least one dose of carbapenems in a tertiary university hospital over a 1-year period (2019). The appropriateness of each prescription was assessed. Results : In total, 96 prescriptions were collected for 75 patients (median age 3 years [interquartile range, IQR : 0–9]). Most prescriptions were empirical (n = 77, 80%) and mainly concerned nosocomial infections (n = 69, 72%). At least one risk factor for extended-spectrum beta-lactamases was found in 48% (n = 46) of cases. The median duration of treatment with carbapenems was 5 days and it was over 7 days in 38% (n = 36) of cases. The use of carbapenems was considered appropriate in 95% (18/19) and 70% (54/77) of cases when therapy was guided by culture results or was empirical, respectively. De-escalation of carbapenem treatment within 72 h occurred in 31% (n = 30) of cases. Conclusion : The use of carbapenems can be optimized in the pediatric population, even when the initial prescription for a carbapenem is considered appropriate. (RA) |
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| Code-barres | Cote | Support | Localisation | Section | Disponibilité | lien web |
|---|---|---|---|---|---|---|
| ESF00505 | PER | Périodique | Bibliothèque ESF | Périodique | Disponible |
